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July 21, 2022Ultrasonic Imaging

A Deep Learning-based Method to Extract Lumen and Media-Adventitia in Intravascular Ultrasound Images

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Key result

IVUS-U-Net++ deep learning accurately segments IVUS lumen and media-adventitia borders with a ~0.92 Jaccard measure.

  • P<.01
  • n=18

Why the study?

Current automated IVUS segmentation relies on manual corrections, which is time-consuming and user-dependent.

Does the IVUS-U-Net++ deep learning model accurately segment lumen and media-adventitia borders in IVUS images compared to ground truth?

Population

1746 IVUS images from 18 patients

Comparison

IVUS-U-Net++ segmentation model vs ground truth

Design

Model development and validation study

Authors

FZFubao ZhuZhengzhou University of Light IndustryZGZhengyuan GaoNanjing Tech UniversityZCZhao ChenCardiac Imaging

Discussion

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Implication

May facilitate automated IVUS analysis in research; leaves open prospective clinical validation.

Structured PICO

Does the IVUS-U-Net++ deep learning model accurately segment lumen and media-adventitia borders in IVUS images compared to ground truth?

P
Population
1746 intravascular ultrasound (IVUS) images from 18 patients
I
Intervention
Deep learning-based automated segmentation method (IVUS-U-Net++) using an encoder-decoder deep architecture with a feature pyramid network
C
Comparator
Ground truth (manual segmentation)
O
Outcome
Jaccard measure (JM) and Hausdorff distance (HD) for lumen and media-adventitia borders, and correlation of 12 clinical parameterssurrogate

Main Result

p-value: p=<.01

The proposed deep learning model IVUS-U-Net++ accurately segments lumen and media-adventitia borders in IVUS images, showing strong agreement with ground truth measurements.

Cite This Study

Zhu et al. (2022) studied Atherosclerosis (n=18). IVUS-U-Net++ deep learning model vs. Ground truth (manual segmentation) was evaluated on Jaccard measure (JM) and Hausdorff distance (HD) for lumen and media-adventitia borders, and correlation of 12 clinical parameters (p=<.01). The IVUS-U-Net++ deep learning model accurately segmented lumen and media-adventitia borders in IVUS images, achieving Jaccard measures of 0.9080 and 0.9199, respectively.

synapsesocial.com/papers/6a091e2b15fb758097d2576dhttps://doi.org/10.1177/01617346221114137
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ImageNet classification with deep convolutional neural networks2017 · 109,538 citations
  2. 2Rethinking the Inception Architecture for Computer Vision2016 · 31,571 citations
  3. 3Fast phase-unwrapping algorithm based on a gray-scale mask and flood fill1998 · 178 citations
  4. 4Robust segmentation of arterial walls in intravascular ultrasound images using Dual Path U-Net2019 · 125 citations