Key result
A mathematical model of tubuloglomerular feedback and the myogenic mechanism predicts autoregulation of GFR and renal blood flow, revealing nonlinear interactions between the two mechanisms.
Authors
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No immediate clinical implications; leaves open translation of modeled nonlinear interactions to human renal physiology.
Marsh et al. (2005) studied Renal blood flow regulation. Mathematical model of tubuloglomerular feedback and myogenic mechanism was evaluated on Autoregulation of GFR and renal blood flow, and TGF-induced oscillations. A mathematical model of tubuloglomerular feedback and the myogenic mechanism predicts autoregulation of GFR and renal blood flow, revealing nonlinear interactions between the two mechanisms.
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