Key result
The ETiCS study is designed to prospectively assess the etiology, titre-course, and effect on survival of beta1-adrenoceptor autoantibodies in patients with human heart disease.
Why the study?
Do acute myocarditis or myocardial infarction trigger autoimmune reactions leading to the generation of cardiac beta1-adrenoceptor autoantibodies?
Observational
Yes
Do acute myocarditis or myocardial infarction trigger autoimmune reactions leading to the generation of cardiac beta1-adrenoceptor autoantibodies?
The ETiCS study is a large clinical diagnostic study designed to investigate the pathophysiology, prevalence, and prognostic significance of cardiac beta1-adrenoceptor autoantibodies in patients with heart disease.
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Whether acute myocarditis or MI trigger beta1-adrenoceptor autoantibodies remains unclear; the ETiCS cohort will prospectively clarify their etiology and survival impact.
Deubner et al. (2010) conducted an observational in Acute myocarditis, myocardial infarction, and cardiomyopathy. Fluorescence-based functional assay for beta1-aabs was evaluated on Etiology, titre-course, and effect on survival of beta1-aabs; prevalence, incidence, persistence, and clearance. The ETiCS study is designed to prospectively assess the etiology, titre-course, and effect on survival of beta1-adrenoceptor autoantibodies in patients with human heart disease.
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