Key result
Patients with diabetic neuropathy had a reduced maximal O2 uptake (83% predicted) compared to nonneuropathic diabetics (104%) and normal subjects (107%; P<0.05), with similar O2 uptake kinetics.
Why the study?
Does diabetic autonomic and sensorineural neuropathy affect O2 uptake kinetics during exercise?
Observational (n=23)
Does diabetic autonomic and sensorineural neuropathy affect O2 uptake kinetics during exercise?
Absolute Event Rate: 83% vs 104%
p-value: p=<0.05
Diabetic neuropathy reduces maximal oxygen uptake but does not impair oxygen uptake kinetics or ventilatory anaerobic threshold during submaximal exercise.
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Diabetic neuropathy may limit exercise capacity via lower peak VO2; cross-sectional data leaves open effects on O2 kinetics.
Kremser et al. (1988) conducted an observational in Diabetic neuropathy (n=23). Diabetic neuropathy vs. Diabetics without neuropathy and normal subjects was evaluated on Maximal O2 uptake (VO2max) % predicted (p=<0.05). Patients with diabetic neuropathy had a reduced maximal O2 uptake (83% predicted) compared to nonneuropathic diabetics (104%) and normal subjects (107%; P<0.05), with similar O2 uptake kinetics.
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