Key result
In type 2 diabetes, muscular oxygen uptake kinetics were faster than heart rate kinetics without medication (p=0.001) or with peripheral meds (p=0.009), but not with centrally acting medication.
Why the study?
Does cardiovascular medication affect heart rate and oxygen uptake kinetics in patients with type 2 diabetes?
Cross-Sectional (n=18)
Does cardiovascular medication affect heart rate and oxygen uptake kinetics in patients with type 2 diabetes?
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Cardiovascular meds may confound kinetics assessment in T2D; leaves open whether standardized tests reliably detect differences.
Koschate et al. (2017) conducted a cross-sectional in Type 2 diabetes (n=18). Cardiovascular medication (centrally or peripherally acting) vs. No cardiovascular medication was evaluated on Maximum in cross-correlation function of muscular oxygen uptake vs. heart rate. In type 2 diabetes, muscular oxygen uptake kinetics were faster than heart rate kinetics without medication (p=0.001) or with peripheral meds (p=0.009), but not with centrally acting medication.
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