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July 22, 1993New England Journal of MedicineOpen Access

Cardiovascular Health and Disease in Women

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Key result

The 1992 NHLBI conference on cardiovascular health in women recommended increased inclusion of diverse women in clinical trials and research focused on sex-specific aspects of heart disease.

Population

Women

Design

Review

Authors

Nanette K. Wenger
Nanette K. WengerPreventive Cardiology
LSLeon SperoffOregon National Primate Research CenterBPBarbara PackardUniversity of Utah

Discussion

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Implication

1992 recommendations remain pertinent amid ongoing underrepresentation; leaves open whether current trials adequately address sex-specific cardiovascular risks.

Structured PICO

P
Population
Women

Highlights the historical underrepresentation of women in cardiovascular research and summarizes 1992 NHLBI conference recommendations to address these gaps.

Limitations

  • Elderly people are underrepresented in research studies, disproportionately excluding women
  • Infrequent inclusion of women in clinical research
  • Few registries available to evaluate outcomes of nonparticipating women

Cite This Study

Wenger et al. (1993) conducted a review in Cardiovascular disease. The 1992 NHLBI conference on cardiovascular health in women recommended increased inclusion of diverse women in clinical trials and research focused on sex-specific aspects of heart disease.

synapsesocial.com/papers/6a092fce4c1e2db30bd2629fhttps://doi.org/10.1056/nejm199307223290406

Topics

Women and heart diseaseCardiovascular prevention
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Gender Differences in the Management of Coronary Artery Disease: Bias or Good Clinical Judgment?1992 · 41 citations
  2. 2Alternative diagnostic strategies for coronary artery disease in women: demonstration of the usefulness and efficiency of probability analysis.1985 · 137 citations
  3. 3The value and limitation of radionuclide angiocardiography with stress in women1983 · 16 citations
  4. 4Hormone Therapy To Prevent Disease and Prolong Life in Postmenopausal Women1992 · 2,359 citations
  5. 5Pregnancy and Congenital Heart Disease1990 · 108 citations