Peroxisome Proliferator-Activated Receptor-α (PPARα) Expression in a Clinical Population of Pakistani Patients with Type 2 Diabetes and Dyslipidemia

Figures

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  Figure 1. The differences in HbA1c (%) and fasting blood glucose between the control, T2DM, and DD groups. Each bar represents the group’s mean. Error bars are ± standard deviation. Note: T2DM and DD data are compared with the control group. * and **** denote statistical significance (p < 0.01; p < 0.0001 respectively). (A): Comparison of BSF (mg/dl), (B); Comparison of HbA1c (mmol/mol).

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  Figure 2. The differences in parameters between the control, T2DM, and DD groups. Each bar represents the group’s mean. Error bars are ± standard deviation Note: T2DM and DD data are compared with the control group. *** and **** denote statistically significant (p < 0.001; p < 0.0001 respectively). (A): Low density lipoprotein (LDL mg/dl); (B): High-density lipoprotein (HDL mg/dl); (C): Total serum cholesterol (tchol mg/dl); (D): Serum triglycerides (TAGS mg/dl).

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  Figure 3. Relationship between HbA1C (%) and biomedical parameters of low-density lipoprotein (LDL mg/dl) (A,B), high-density lipoprotein (HDL mg/dl) (C,D), and total serum cholesterol (tchol mg/dl) (E,F) in T2DM and DD group. Each dot of the scattered plot represents the data of individual participants.

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  Figure 4. Relationship between HbA1C (%) and biomedical parameters of fasting blood glucose (mg/dl) (A,B), serum triglycerides (TAGS mg/dl) (C,D) in T2DM and DD group. Each dot of the scattered plot represents the data of individual participants.

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  Figure 5. The mean Ct value of PPARα expression in the control, T2DM, and DD groups. Each black dot indicates the mean Ct value of an individual sample. *** denote statistical significance (p < 0.001). Data were collected from our previous study. (Arif M, Siddique K, Majeed A. Comparison of expression of PPARα and SCARB1 gene in type 2 diabetic and type 2 diabetic dyslipidemia patients. Medicina. (Submitted and under review; Manuscript ID medicina-1845712).

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  Figure 6. Relationship between PPARα Ct mean and biomedical parameters of total serum cholesterol (tchol mg/dl) (A), serum triglycerides (TAGS mg/dl) (B), low-density lipoprotein (LDL mg/dl) and high-density lipoprotein (HDL mg/dl) (C) in T2DM group. Each dot of the scattered plot represents the data of individual participants.

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  Figure 7. Relationship between PPARα Ct mean and biomedical parameters of total serum cholesterol (tchol mg/dl) (A), serum triglycerides (TAGS mg/dl) (B), low-density lipoprotein (LDL mg/dl) and high-density lipoprotein (HDL mg/dl) (C) in DD group. Each dot of the scattered plot represents the data of individual participants.