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May 1, 1996Journal of Biological ChemistryOpen Access

Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts

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Authors

FDFred H. DrakeHalozyme Therapeutics (United States)RDRobert A. DoddsProvidence HospitalIJIan E. JamesRoyal National Hospital for Rheumatic Diseases

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Cite This Study

Drake et al. (1996) studied this question.

synapsesocial.com/papers/6a0932f04c1e2db30bd26510https://doi.org/10.1074/jbc.271.21.12511
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Also Consider

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  1. 1Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas1995 · 113 citations
  2. 2Human Cathepsin O2, a Novel Cysteine Protease Highly Expressed in Osteoclastomas and Ovary Molecular Cloning, Sequencing and Tissue Distribution1995 · 243 citations
  3. 3Inhibition of bone resrption by selctive inactivators of cysteine proteinases1994 · 115 citations
  4. 4Lysosomal cysteine and aspartic proteinases, acid phosphatase, and an endogenous cysteine proteinase inhibitor, cystatin-beta, in rat osteoclasts.1993 · 83 citations
  5. 5Effect of disruption of actin filaments by Clostridium botulinum C2 toxin on insulin secretion in HIT-T15 cells and pancreatic islets.1994 · 150 citations