Key result
Single-pulse irreversible electroporation achieves acute PVI in 100% of targeted veins without complications.
Why the study?
Irreversible electroporation is a promising nonthermal ablation technology, but its feasibility and safety for pulmonary vein isolation with a single pulse in atrial fibrillation required investigation.
Does single pulse irreversible electroporation achieve safe and feasible pulmonary vein isolation in patients with symptomatic atrial fibrillation?
Does single pulse irreversible electroporation achieve safe and feasible pulmonary vein isolation in patients with symptomatic atrial fibrillation?
Single pulse irreversible electroporation is a feasible and safe novel nonthermal ablation modality for achieving acute pulmonary vein isolation in patients with atrial fibrillation.
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Hypothesis-generating for single-pulse IRE in acute PVI; prospective trials needed before clinical adoption.
Loh et al. (2020) studied Symptomatic paroxysmal or persistent atrial fibrillation (n=10). Single pulse irreversible electroporation (IRE) was evaluated on Successful pulmonary vein isolation and periprocedural complications. Single pulse irreversible electroporation safely achieved acute bidirectional electrical pulmonary vein isolation in 100% of targeted veins (40/40) with no periprocedural complications.
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