Key result
Sleep induces similar hemodynamic changes driven by diminished peripheral resistance in normal and hypertensive subjects, though hypertensives maintain decreased baroreflex sensitivity.
Why the study?
How do haemodynamic parameters change during sleep in normal and hypertensive subjects?
How do haemodynamic parameters change during sleep in normal and hypertensive subjects?
The fall in blood pressure during sleep is driven by diminished peripheral resistance, with similar haemodynamic changes in normal and hypertensive subjects, though hypertensives have decreased baroreflex sensitivity.
Supports mechanistic insights into nocturnal BP fall; leaves open whether baroreflex differences affect CV risk during sleep.
The fall of blood pressure accompanying sleep in man is largely due to a diminished peripheral resistance. Subjects with normal and raised arterial pressure show qualitatively and quantitatively similar haemodynamic changes during sleep, except that the baroreflex sensitivity in hypertensives is decreased, both awake and asleep.
No takes yet. Share an insight, caveat, or question.
Bristow et al. (1969) studied this question. Sleep induces similar hemodynamic changes driven by diminished peripheral resistance in normal and hypertensive subjects, though hypertensives maintain decreased baroreflex sensitivity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: