Activation of TREK ‐1 and TREK ‐2 Two‐Pore Domain Potassium Channels by the K v 4 Channel Modulator, NS5806

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Effect of the Itoactivator NS5806 on cloned Kv4 channels depends on the accessory protein KChIP22010 · 47 citations
2. 2A pharmacological master key mechanism that unlocks the selectivity filter gate in K + channels2019 · 139 citations
3. 3A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome2008 · 116 citations
4. 4A‐type K + channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons2012 · 92 citations
5. 5Auxiliary subunits control biophysical properties and response to compound NS5806 of the Kv4 potassium channel complex2019 · 14 citations