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May 17, 2026Russian Cardiology BulletinOpen Access

Recurrent bleeding in patients with atrial fibrillation receiving anticoagulation: fundamental and promising aspects of research

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Authors

KIKh.D. ImomkulovNational Medical Research Center of CardiologyEKE. S. KropachevaNational Medical Research Center of CardiologyADA.B. DobrovolskyNational Medical Research Center of Cardiology

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Implication

Review analyzes recurrent bleeding risks in atrial fibrillation patients on anticoagulants, highlighting key predictors.

Key Points

  • This review aims to explore recurrent bleeding in atrial fibrillation patients on anticoagulation, identifying risk factors and predictors.
  • Systematic analysis of clinical data on recurrent bleeding incidence in patients with atrial fibrillation.
  • Identification and classification of clinical and laboratory risk factors related to bleeding.
  • Discussion of fibrin structure visualization methods to understand potential mechanisms behind recurrent bleeding.
  • 15-20% of patients experience recurrent hemorrhagic complications despite anticoagulation adjustments.
  • Identification of both modifiable and unmodifiable risk factors for recurrent bleeding.
  • Findings support the hypothesis that unstable fibrin clots contribute to recurrent bleeding.

Cite This Study

Imomkulov et al. (2026) studied this question.

synapsesocial.com/papers/6a095b8e7880e6d24efe165chttps://doi.org/10.17116/cardiobulletin20262102122
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anticoagulation Use and Clinical Outcomes After Major Bleeding on Dabigatran or Warfarin in Atrial Fibrillation2016 · 45 citations
  2. 2Rates of rebleeding, thrombosis and mortality associated with resumption of anticoagulant therapy after anticoagulant-related bleeding2021 · 22 citations
  3. 3Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: the IAC study2021 · 72 citations
  4. 4Association between genetic polymorphisms in fibrinogen genes and bleeding risk in patients treated with direct oral anticoagulants2023 · 4 citations
  5. 5Resuming anticoagulants after anticoagulation-associated intracranial haemorrhage: systematic review and meta-analysis2018 · 41 citations