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May 17, 2026Diabetes Epidemiology and ManagementOpen Access

Prevalence of comorbidities associated with type 2 diabetes and prediabetes and a case-control analysis of the emergence of new comorbidities in 2007 - 2019

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Authors

MLMerja LaineHJHannu JärveläinenMVMarkku Vielma

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Overview

Case-control analysis reveals high prevalence of cardiovascular diseases and CKD in type 2 diabetes, indicating the importance of treatment modification.

Key Points

  • This study investigates the prevalence of cardiovascular diseases and chronic kidney disease among patients with type 2 diabetes and prediabetes.
  • Analyzed real-world data from Turku University Hospital between 2005 and 2019.
  • Included cohorts of 37,209 patients with T2DM and 42,554 with prediabetes in 2019.
  • Used logistic regression to analyze the emergence of comorbidities.
  • T2DM patients showed a higher prevalence of comorbidities compared to those with prediabetes.
  • The highest risk ratio for complications was observed in CKD (OR 1.006, 95% CI 1.005–1.006).
  • Use of GLP-1 receptor agonists and SGLT2 inhibitors was linked to lower comorbidity risk (p<0.0001).

Cite This Study

Laine et al. (2026) studied this question.

synapsesocial.com/papers/6a095c037880e6d24efe1e88https://doi.org/10.1016/j.deman.2026.100318
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