What question did this study set out to answer?

This research aims to optimize the architecture of Nicotiana benthamiana for enhanced recombinant protein production in vertical farming settings.

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

View Full Paper

Ask AI

Bookmark

Authors

Randomized trial demonstrates improved protein yields in compact genetically modified plants, suggesting efficient indoor farming solutions.

This research aims to optimize the architecture of Nicotiana benthamiana for enhanced recombinant protein production in vertical farming settings.
Used CRISPR/Cas9 gene editing to create ΔCCD mutant lines in Nicotiana benthamiana.
Targeted suppression of strigolactone synthesis via Carotenoid cleavage dioxygenase 7 and 8.
Analyzed changes in plant architecture and protein yields.
ΔCCD mutants showed a 45%-50% reduction in spatial footprint.
Knocking out CCD7 or CCD8 resulted in altered auxin/cytokinin ratios without impacting growth rates.
Recombinant protein yields were maintained in mutant lines, demonstrated by GFP and rituximab production.

Giroux et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark

Randomized trial demonstrates improved protein yields in compact genetically modified plants, suggesting efficient indoor farming solutions.