Examining short-term and long-term outcomes in octogenarians undergoing isolated surgical aortic valve replacement.

BACKGROUND: As the transcatheter approach to aortic valve disease become more common, the role of surgical aortic valve replacement (SAVR), particularly in older patients, is increasingly contentious. This study aimed to examine short-term and long-term outcomes in octogenarians undergoing isolated SAVR. METHODS: All consecutive patients aged 80 years and over undergoing isolated first-time SAVR in two cardiac surgery centres between 1997 and 2019 were included. Primary outcomes were in-hospital, 1-year and 5-year mortality and overall survival. Secondary outcomes were re-exploration, post-operative renal replacement therapy, post-operative stroke, post-operative permanent pacemaker implantation and post-operative length of stay (PLOS). The multivariate Cox regression analysis was used to identify variables independently associated with overall survival. RESULTS: = 473/502). Median follow-up time was 77 (44-101) months and estimated median overall survival was 81 (76-86) months. CONCLUSIONS: SAVR remains a safe operation in octogenarian patients. Findings from this study suggest that for appropriately selected patients, SAVR can provide durable long-term benefit and should still be considered an appropriate treatment strategy.