What question did this study set out to answer?

This study aims to characterize ginseng adventitious root polysaccharides and evaluate their effects on insulin resistance and mechanisms.

May 17, 2026eFoodOpen Access

Structural Characterization of Ginseng Adventitious Root Polysaccharides and Their Effects on Ameliorating Insulin Resistance

View Full Paper

Ask AI

Bookmark

Authors

Randomized trial shows ginseng adventitious root polysaccharides improve insulin resistance, indicating potential health benefits.

This study aims to characterize ginseng adventitious root polysaccharides and evaluate their effects on insulin resistance and mechanisms.
Purified ginseng adventitious root polysaccharides through hot water extraction, ethanol precipitation, and column chromatography.
Evaluated effects on insulin resistance in IR-HepG2 cells and in mice induced with a high-fat diet and streptozotocin.
Assessed metabolic parameters, liver pathology, oxidative stress, and the Nrf2/Keap1 pathway.
GARP improved glucose utilization and lipid metabolism in vitro and in vivo.
Alleviated oxidative stress and liver injury, resulting in improved insulin resistance.
Activation of the Nrf2/Keap1 signaling pathway was observed.

Yang et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark