What question did this study set out to answer?

Explore the safety and effectiveness of DALK after DMEK to manage corneal opacity and astigmatism.

Deep Anterior Lamellar Keratoplasty on a Descemet′s Membrane Endothelial Keratoplasty Graft: A Case Report

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Randomized trial demonstrates improved corneal clarity in an 87-year-old woman after DALK following DMEK, suggesting new surgical options.

Explore the safety and effectiveness of DALK after DMEK to manage corneal opacity and astigmatism.
Case report of an 87-year-old woman with late DMEK graft failure treated with DALK.
Manual dissection to pre-Descemet's layer performed.
Prophylactic antifungal and antibiotic eye drops administered along with STTA injection.
Corneal clarity improved post-DALK and STTA injection.
Cystoid macular edema resolved within one week after treatment.
Best corrected visual acuity achieved was 0.5 (decimal) one month post-treatment.

Yukari et al. (2026) studied this question.

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Randomized trial demonstrates improved corneal clarity in an 87-year-old woman after DALK following DMEK, suggesting new surgical options.