Effect of diuretics, angiotensin receptor blockers and beta-blockers on the quality of life among heart failure patients in a tertiary care hospital in North India

Objectives Patients with chronic heart failure (CHF) often experience poor quality of life as a result of difficulties in performing daily activities and impaired psychological health. This study aims to assess the association between the drugs and quality of life in CHF patients. Methods The study included CHF patients admitted to Kalpana Chawla Government Medical College, Karnal, over a two-month period. Quality of life was assessed using the Minnesota Living with Heart Failure questionnaire (MLHFQ) after 4 weeks of drug therapy. Results Among 67 enrolled CHF patients, the majority were aged 50–59 years, and females constituted most of the study population. Most participants (80.6 %) had lower MLHFQ scores. Patients on the four-drug regimen had a lower median score of 14 (IQR: 9–20), with a mean score of 14.69 ± 8.19, compared with other groups. There were no statistically significant differences in total or domain-specific scores between treatment groups (p>0.05). Conclusions Although lower MLHFQ scores were observed in patients receiving multidrug therapy, this indicates an association rather than causal effects and should be interpreted with caution. Further large-scale, prospective studies are required to evaluate the relationship between drugs and quality of life in CHF patients.