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December 1, 2021The Journal of V N Karazin Kharkiv National University series MedicineOpen Access

Quality of life and medication adherence in patients with chronic heart failure associated with arterial hypertension and chronic kidney disease

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Key result

No clinical data found in the provided text, which is a software manual for Open Journal Systems.

Why the study?

Poor adherence worsens chronic heart failure manifestations and hospitalizations, prompting the study to characterize quality of life and evaluate the effect of medication adherence in elderly patients with HFpEF, arterial hypertension, and chronic kidney disease.

Does medication adherence improve quality of life in patients with chronic heart failure with preserved ejection fraction, arterial hypertension, and chronic kidney disease?

Population

122 patients aged 64 [62; 68] years with chronic heart failure, arterial hypertension, and chronic kidney disease

Comparison

Adherent cohort vs non-adherent cohort based on medication adherence level

Design

Prospective study

Follow-up

12 months

Authors

ОХО. О. ХанюковMinistry of Education and ScienceOSO. V. SmolianovaValeo (France)

Discussion

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Member takes

Overview

Non-adherence linked to worse QoL in HFpEF with hypertension and CKD; hypothesis-generating and requires randomized trials before informing care.

Structured PICO

Does medication adherence improve quality of life in patients with chronic heart failure with preserved ejection fraction, arterial hypertension, and chronic kidney disease?

P
Population
122 patients aged 64 [62; 68] years with chronic heart failure with preserved ejection fraction (HFpEF) on the background of arterial hypertension and chronic kidney disease.
I
Intervention
Medication adherence (adherent cohort)
C
Comparator
Non-adherence to medication (non-adherent cohort)
O
Outcome
Quality of life assessed by the Minnesota Living with Heart Failure Questionnaire during hospitalization, after 6 months, and after 12 monthspatient reported

Poor medication adherence in patients with HFpEF, hypertension, and chronic kidney disease is associated with worse disease compensation and significantly deteriorated quality of life up to 12 months.

Cite This Study

Ханюков et al. (2021) studied this question. No clinical data found in the provided text, which is a software manual for Open Journal Systems.

synapsesocial.com/papers/6a9edde2ba6fb3588c8c4d9ehttps://doi.org/10.26565/2313-6693-2021-43-05
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Factors Associated With Nonadherence to Cardiovascular Medications2019 · 44 citations
  2. 2Polypharmacy in Older Adults Hospitalized for Heart Failure2020 · 183 citations
  3. 3Valuing health-related quality of life in heart failure: a systematic review of methods to derive quality-adjusted life years (QALYs) in trial-based cost–utility analyses2019 · 18 citations
  4. 42016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure2016 · 11,597 citations
  5. 5The Impact of Pharmacist/Physician Care on Quality of Life in Elderly Heart Failure Patients: Results of the PHARM-CHF Randomized Controlled Trial2020 · 24 citations