Why the study?
Do initial echocardiographic findings predict long-term prognosis in patients with peripartum cardiomyopathy?
Cohort (n=33)
Do initial echocardiographic findings predict long-term prognosis in patients with peripartum cardiomyopathy?
Initial LVEF >27% and LVESD <=5.5 cm are predictive of left ventricular function recovery in patients with peripartum cardiomyopathy.
Answers are grounded in this paper and cite their sources.
May aid risk stratification in peripartum cardiomyopathy; leaves open need for prospective validation before guiding care.
OBJECTIVES: To evaluate the long-term follow-up results of patients with peripartum cardiomyopathy and assess the echocardiographic findings relating to prognosis at time of diagnosis. METHODS: Thirty-three patients diagnosed with peripartum cardiomyopathy and hospitalized between 1995 and 2007 were analyzed. Initial echocardiographic data were recorded and long-term clinical status was evaluated. RESULTS: Eight (24%) patients recovered completely, 10 (30%) died, 2 (6%) underwent heart transplants, and 13 (39%) were left with persistent left ventricular dysfunction. Cut-off values for initial left ventricular end-systolic diameter (< or =5.5 cm) and left ventricular ejection fraction (>27%) were obtained from patients who had completely recovered. CONCLUSION: Cut-off values for initial left ventricular ejection fraction of >27% and left ventricular end-systolic diameter of < or =5.5 cm may predict recovery of left ventricle function.
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Duran et al. (2008) conducted a cohort in Peripartum cardiomyopathy (n=33). Initial echocardiographic parameters (LVEF and LV end-systolic diameter) was evaluated on Long-term clinical status and recovery of left ventricular function.
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