Key result
Treated primary hypertension resulted in renal function deterioration in 15% of patients, with black patients twice as likely as white patients to experience creatinine elevations (23% vs 11%).
Cohort (n=94)
Renal function may deteriorate in a subset of patients with treated essential hypertension despite good blood pressure control, with higher risk observed in older, black, and laborer patients.
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May warrant enhanced renal monitoring in black patients on antihypertensives; leaves open prospective validation of risk factors.
Rostand et al. (1989) conducted a cohort in Treated primary hypertension (n=94). Treated primary hypertension was evaluated on Increase in serum creatinine concentrations (≥0.4 mg/dL). Treated primary hypertension resulted in renal function deterioration in 15% of patients, with black patients twice as likely as white patients to experience creatinine elevations (23% vs 11%).
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