Comparison of Methods of Mean Blood Pressure Calculation Using Ambulatory Blood Pressure Monitoring Results

Ambulatory blood pressure monitoring (ABPM) is a modern method of BP investigation. However, only some ABPM parameters, as diurnal systolic BP (SBP) and diastolic BP (DBP), are used now as the diagnostic guide according to international recommendations. It is pure knowledge in clinical practice about usage and calculation of mean blood pressure (MBP). Such parameter is the steady flow of blood through the aorta and its arteries and equals the cardiac output multiplied by vascular resistance [1], according to some clinical studies may have predictable value as SBP or DBP, however there is no clinical evidence about these parameters, as information how to calculate in ABPM. The aim of the study is to compare the mean blood pressure calculated by two methods using ABPM parameters. We selected 20 ambulatory blood pressure monitoring (ABPM) patients (median of age 60 [56; 64] years, 65 % women). ABPM was recorded using a bifunctional device (Incart, S.-P., RF). We calculated MBP as [[(2×DBP)+SBP]/3] [2] and as [DBP+[0.01×exp(4,14-40,74/HR)] ×PP] [3], Formula 1 and Formula 2, respectively. The analysis of difference between results of MBP measurements calculated by two methods was performed using the Bland and Altman method. The data show, that MBP calculated by Formula 1 and Formula 2 are as 87.7 [83.2−90.5] and 91.1 [85.4−93.5] mm Hg, respectively. The limits of agreements for the MBP were 0,49/5,91. In general, based on the findings of the current study, the measurements of MBP calculated using different formulas show good agreement. Further studies need to have more clinical evidence to analyze the result