Key result
In hypertensive patients with OSAS, the prevalence of non-dipping and reverse dipping blood pressure patterns was high and significantly associated with a history of hypertension (p<0.05).
Why the study?
Arterial hypertension is the main cardiovascular consequence of obstructive sleep apnea syndrome, motivating an evaluation of nocturnal blood pressure patterns in hypertensive patients with OSAS in Angola.
Cross-Sectional (n=70)
No
p-value: p=<0.05
In hypertensive patients with OSAS in Angola, there is a high prevalence of abnormal nocturnal blood pressure patterns (non-dipping and reverse dipping).
Abnormal nocturnal BP patterns in hypertensive OSAS should not yet change practice; leaves open need for longitudinal outcome studies.
The main cardiovascular consequence of Obstructive Sleep Apnea Syndrome (OSAS) is arterial hypertension (AH), considered since 2003 a second cause of AH. This study aimed to evaluate nocturnal blood pressure patterns (BPP) in hypertensive patients with OSAS in Angola. A descriptive, cross-sectional observational study was carried out in a private clinic in Angola. Demographic and clinical variables, polysomnography, and ABPM parameters were included. Patients were classified as a dippers, non-dippers, and reverse dippers. One-way ANOVA test, Kruskal-Walli’s test, and chi-square test were used as appropriate. The sample consisted of 70 individuals: 39(55.7%) were male. The mean age was 53.63±9.14 years and the BMI was 35.82 ± 6.57 kg/m2. An association between patients with a past medical history of hypertension and BPP was found (p<0.05). Mean O2 saturation was significantly lower in the reverse dippers (p=0.25). Although insignificantly, the dippers were younger and less obese. In contrast, the proportion of smokers and diabetics was higher in the reverse dippers. No correlation was found between the apnea-hypopnea index, the mean blood pressure, and the Epworth sleepiness scale. In the present study, the prevalence of non-dipping and reverse dipping patterns was high. It needs to be confirmed with future prospective studies.
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Caetano et al. (2023) conducted a cross-sectional in Hypertensive patients with Obstructive Sleep Apnea Syndrome (n=70). In hypertensive patients with OSAS, the prevalence of non-dipping and reverse dipping blood pressure patterns was high and significantly associated with a history of hypertension (p<0.05).
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