What question did this study set out to answer?

Compare the parasitological efficacy and cost-effectiveness of mass, targeted, and selective levamisole chemotherapy strategies for community-level control of Ascaris lumbricoides.

August 1, 1996Journal of Parasitology

A Cost-Effectiveness Analysis of Anthelminthic Intervention for Community Control of Soil-Transmitted Helminth Infection: Levamisole and Ascaris lumbricoides

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Authors

CHCelia V. Holland EOEmma O’Shea SAS. O. Asaolu

Discussion

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Overview

Comparative intervention trial demonstrates greater cost-effectiveness of mass and targeted deworming over selective treatment in rural communities, highlighting simpler delivery strategies.

Key Points

Compare the parasitological efficacy and cost-effectiveness of mass, targeted, and selective levamisole chemotherapy strategies for community-level control of Ascaris lumbricoides.
Assigned three distinct treatment strategies across three rural Nigerian communities: selective treatment of the top 20% most heavily infected, targeted treatment of children aged 2–15 years, and mass treatment of all residents excluding pregnant women and infants under 1 year.
Assessed infection intensity (eggs per gram) immediately prior to treatment and 3 months post-intervention.
Analyzed retrospective expenditures—including manpower, materials, pharmaceuticals, and transportation—to determine cost per person treated and cost per 1,000 egg reduction.
Mass and targeted chemotherapy approaches proved considerably more cost-effective than the selective treatment strategy.
Selective chemotherapy required substantial diagnostic resources and manpower, diminishing overall economic efficiency compared to broader community-based delivery models.

Cite This Study

Holland et al. (1996) studied this question.

synapsesocial.com/papers/6a09f74200274e073d45cabd https://doi.org/10.2307/3283775

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August 1, 1996Journal of Parasitology

A Cost-Effectiveness Analysis of Anthelminthic Intervention for Community Control of Soil-Transmitted Helminth Infection: Levamisole and Ascaris lumbricoides

View Full Paper

Ask AI

Bookmark

Authors

CHCelia V. Holland EOEmma O’Shea SAS. O. Asaolu

Discussion

Member takes

Overview

Comparative intervention trial demonstrates greater cost-effectiveness of mass and targeted deworming over selective treatment in rural communities, highlighting simpler delivery strategies.

Key Points

Compare the parasitological efficacy and cost-effectiveness of mass, targeted, and selective levamisole chemotherapy strategies for community-level control of Ascaris lumbricoides.
Assigned three distinct treatment strategies across three rural Nigerian communities: selective treatment of the top 20% most heavily infected, targeted treatment of children aged 2–15 years, and mass treatment of all residents excluding pregnant women and infants under 1 year.
Assessed infection intensity (eggs per gram) immediately prior to treatment and 3 months post-intervention.
Analyzed retrospective expenditures—including manpower, materials, pharmaceuticals, and transportation—to determine cost per person treated and cost per 1,000 egg reduction.
Mass and targeted chemotherapy approaches proved considerably more cost-effective than the selective treatment strategy.
Selective chemotherapy required substantial diagnostic resources and manpower, diminishing overall economic efficiency compared to broader community-based delivery models.

Cite This Study

Holland et al. (1996) studied this question.

synapsesocial.com/papers/6a09f74200274e073d45cabd https://doi.org/10.2307/3283775

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

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