Key result
Single channel recording of tunicate egg cells showed that anomalous K current blocking kinetics by Na, Cs, and Sr are consistent with first-order transitions between open and closed states.
Population
Tunicate egg cell
Design
Preclinical
Authors
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Characterizes anomalous K rectifier kinetics in a model system; leaves open translation to mammalian cardiac channels.
This basic science study characterizes the single-channel blocking kinetics and conductance of the anomalous potassium rectifier in tunicate egg cells.
Yasuo Fukushima (1982) studied this question. Single channel recording of tunicate egg cells showed that anomalous K current blocking kinetics by Na, Cs, and Sr are consistent with first-order transitions between open and closed states.
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