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Methodological study derives the asymptotic joint distribution of sequential survival statistics with staggered entry and censoring, enabling repeated significance testing over real time.
The asymptotic joint distribution of a class of sequentially computed statistics used in survival analysis is derived when the individuals under study enter serially and are subject to random loss to follow-up. These results are used for constructing repeated significance tests over real time.
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Anastasios A. Tsiatis (1982) studied this question.
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