Key result
The number of instrumental activities of daily living (IADL) dependencies was significantly associated with major depression in older heart failure patients (P=0.016), whereas ADL dependencies were not.
Why the study?
Is there an association between ADL/IADL dependence and major depression in older primary care patients with heart failure?
Cross-Sectional (n=415)
Is there an association between ADL/IADL dependence and major depression in older primary care patients with heart failure?
In older patients with heart failure, an increasing number of instrumental activities of daily living (IADL) dependencies is significantly associated with a higher likelihood of major depression.
Answers are grounded in this paper and cite their sources.
Should not yet change screening practices; hypothesis-generating for IADL-specific depression links in older HF.
The purpose of this study was to examine the association between dependence in activities of daily living (ADL) and instrumental ADL (IADL) and major depression among 415 community-dwelling primary care patients age 65+ with heart failure and significant ADL or IADL dependence. Main findings include (1) a progressive increase in depression prevalence from 0% for no IADL dependence to about 40% for 6 IADL dependencies (P < .001), (2) a steady rise in depression prevalence to 40% for 6 ADL dependencies following a "floor effect" at about 10% for 0 to 2 ADL dependencies (P < .001), and (3) the association in a logistic regression model of major depression with number of IADL dependencies (P = .016) but not with number of ADL dependencies (P = .602). Our principal conclusion is that the progressively greater likelihood of major depression as the number of IADL dependencies increases has important clinical, personal, social, and public health relevance.
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Friedman et al. (2008) conducted a cross-sectional in Heart failure and significant ADL or IADL dependence (n=415). Number of IADL and ADL dependencies vs. Fewer or no dependencies was evaluated on Major depression (p=0.016). The number of instrumental activities of daily living (IADL) dependencies was significantly associated with major depression in older heart failure patients (P=0.016), whereas ADL dependencies were not.
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