November 1, 1991Psychosomatic Medicine
Platelets and coronary heart disease: potential psychophysiologic mechanisms.
Key result
Platelet reactivity to psychological stress is proposed as a major mechanism in coronary events, supported by literature indicating that platelet activity is increased by emotional stress.
Design
Review
Authors
Discussion
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Member takes
Implication
Should not yet change practice; hypothesis-generating for stress-platelet pathways in coronary events.
PICO
P
Population
Coronary heart disease
I
Intervention / Comparator
Psychological stress
This review highlights the potential role of platelet reactivity to psychological stress as a major mechanism precipitating acute coronary events.
Cite This Study
Markovitz et al. (1991) conducted a review in Coronary heart disease. Psychological stress was evaluated. Platelet reactivity to psychological stress is proposed as a major mechanism in coronary events, supported by literature indicating that platelet activity is increased by emotional stress.