Key result
Severe preeclampsia linked to acute LV failure and transient Takotsubo syndrome during pregnancy.
Why the study?
The mechanisms of takotsubo syndrome, also known as stress-induced cardiomyopathy, are not fully understood.
Case Report (n=1)
Takotsubo syndrome can present as acute heart failure in pregnant women with severe preeclampsia, with typical transient regional wall motion abnormalities that resolve completely.
Should not change management of heart failure in preeclampsia; hypothesis-generating case needing confirmation in prospective studies.
The mechanisms of takotsubo syndrome, better known as stress-induced cardiomyopathy, are not fully understood. The article presents a clinical case of the development of acute left ventricular failure in a 39-year-old pregnancy against the background of severe preeclampsia. Echocardiography revealed a decrease in global myocardial contractility, hypo-akinesia of the apex and all median parts of the left ventricle, hyperkinesis of the basal parts. After 2 weeks, myocardial contractility was normal, no contractility impairment was found. Two months after the acute episode of the disease, magnetic resonance imaging of the heart was performed, according to which no pathological changes were detected. Based on the clinical picture, electrocardiogram changes, laboratory data and typical transient echocardiographic changes, it was suggested that the patient had takotsubo syndrome.
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Болдуева et al. (2022) conducted a case report in Takotsubo syndrome (n=1). Severe preeclampsia in a 39-year-old pregnant woman was associated with acute left ventricular failure and transient echocardiographic changes typical of Takotsubo syndrome that resolved in 2 weeks.
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