Key result
Resolving childhood excess weight by adulthood carries no increased cardiometabolic risk versus lifelong normal weight.
Why the study?
The effects of childhood excess weight on adult cardiometabolic risk factors, and whether returning to normal adult weight mitigates these effects, were unresolved in a Chinese population.
Does childhood excess weight status increase adult cardiometabolic risk factors in a Chinese population?
Population
541 participants measured in childhood and reassessed in adulthood in China
Comparison
Childhood BMI z-score quartiles and long-term weight status changes
Design
Cohort study
Follow-up
Mean 14.9-year
Authors
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Adult weight normalization may offset childhood excess weight risks; leaves open need for interventional confirmation.
Cohort (n=541)
Yes
Does childhood excess weight status increase adult cardiometabolic risk factors in a Chinese population?
Effect estimate: RR 1.10 (95% CI 0.87-1.38)
p-value: p=0.440
Childhood excess weight increases adult cardiometabolic risks, but these effects are mitigated if adult weight status returns to normalcy.
Fan et al. (2020) conducted a cohort in Cardiometabolic risk factors (n=541). Childhood excess weight status returning to normal in adulthood (child BMI z-score ≥ 75th percentile and adult BMI z-score < 75th percentile) vs. Normal weight in both childhood and adulthood (child and adult BMI z-scores < 75th percentile) was evaluated on ≥1 adult cardiovascular risk factors (RR 1.10, 95% CI 0.87-1.38, p=0.440). Childhood excess weight status returning to normal in adulthood did not significantly increase the risk of adult cardiometabolic risk factors compared to maintaining normal weight in both periods (RR 1.10).
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