Why the study?
Mitral valve repair with a large anterior-posterior diameter and redundant tissue is challenging, and mid-term results using the Medtronic Simulus annuloplasty ring had not been reported.
Does mitral valve repair with the Medtronic Simulus annuloplasty ring provide safe and effective mid-term outcomes in patients with degenerative mitral regurgitation, large annuli, and abundant leaflet tissue?
Does mitral valve repair with the Medtronic Simulus annuloplasty ring provide safe and effective mid-term outcomes in patients with degenerative mitral regurgitation, large annuli, and abundant leaflet tissue?
The Medtronic Simulus annuloplasty ring demonstrates excellent mid-term survival and low rates of recurrent mitral regurgitation or reoperation in patients with large annuli and abundant leaflet tissue.
Supports mid-term durability of Simulus annuloplasty in large-annulus degenerative MR; leaves open randomized comparisons to other rings.
Backround: Mitral valve (MV) repair in the case of a large anterior-posterior diameter and redundant valve tissue remains challenging and favors repair with a ring that exhibits a large anterior-posterior diameter. Compared to other available rings, the Medtronic Simulus annuloplasty ring shows the largest anterior-posterior diameter. This study reports for the first time mid-term results using this annuloplasty ring. Methods: Between 11/2015 and 12/2019, a total of 378 patients underwent MV repair for degenerative mitral regurgitation using the Medtronic Simulus ring, according to the following selection criteria: large MV annuli, abundant leaflet tissue (i.e., Barlow disease), and risk for SAM. Results: Overall survival after 5 years was 90.8 ± 4.6%. Five patients required valve-related reoperations because of ring dehiscence (n = 1), progression of native valve disease (n = 2), dehiscence of quadrangular resection suture (n = 1), and endocarditis (n = 1). The cumulative incidence of valve-related reoperation at 5 years was 1.3 ± 0.5%. At latest follow-up, echocardiography demonstrated excellent valve function with no/mild MR in 299 patients (94.6%). Two patients (0.6%) had more than moderate MR. No patient developed SAM after repair. Conclusion: Repair of MV with large annuli and abundant leaflet tissue with the Medtronic Simulus annuloplasty ring shows excellent mid-term results regarding reoperation rates and recurrent MR.
No takes yet. Share an insight, caveat, or question.
Sideris et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: