Why the study?
What are the clinical characteristics and risk factors associated with peri-operative Takotsubo syndrome in patients undergoing non-cardiac surgery?
Population
100 adult patients who underwent in-hospital non-cardiac surgeries between January 2017 and December 2020.
Design
Case-control
Follow-up
Peri-operative period / in-hospital
Key result
Pre-operative leucocyte count >10 × 10^9/L, haemoglobin <120 g/L, and an RCRI score ≥1 were independently associated with peri-operative Takotsubo syndrome after non-cardiac surgery.
Authors
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May enhance pTTS prediction when added to RCRI; hypothesis-generating from case-control data and needs prospective validation.
Case-Control (n=100)
No
What are the clinical characteristics and risk factors associated with peri-operative Takotsubo syndrome in patients undergoing non-cardiac surgery?
Peri-operative Takotsubo syndrome is a rare but severe complication of non-cardiac surgery, and its prediction can be significantly improved by adding leukocyte count and hemoglobin levels to the standard Revised Cardiac Risk Index.
Effect estimate: OR 4.59 (95% CI 1.10-19.15)
p-value: p=0.036
Shang et al. (2022) conducted a case-control in Peri-operative Takotsubo syndrome (pTTS) (n=100). Pre-operative risk factors (Leucocyte count, Haemoglobin, RCRI score) vs. Matched controls without pTTS was evaluated on Association of leucocyte count >10 × 10^9/L with peri-operative Takotsubo syndrome (OR 4.59, 95% CI 1.10-19.15, p=0.036). Pre-operative leucocyte count >10 × 10^9/L, haemoglobin <120 g/L, and an RCRI score ≥1 were independently associated with peri-operative Takotsubo syndrome after non-cardiac surgery.
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