Key result
Three-lead measurement of QTc dispersion using quasi-orthogonal leads successfully differentiated post-MI deaths from survivors (-2.6 vs 26.9 msec; P=0.003), similar to standard 12-lead ECGs.
Why the study?
Does a three-lead measurement of QTc dispersion provide the same prognostic information as a standard 12-lead measurement in post-myocardial infarction patients?
Population
Patients with 270 12-lead ECGs recorded at least 1 month after myocardial infarction, comparing those who…
Comparison
Calculation of QTc dispersion using three-lead… vs Standard 12-lead measurement of QTc dispersion
Design
Cohort
Authors
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Three-lead QTc dispersion may simplify post-MI risk stratification; hypothesis-generating and leaves open prospective validation before clinical use.
Observational (n=270)
Does a three-lead measurement of QTc dispersion provide the same prognostic information as a standard 12-lead measurement in post-myocardial infarction patients?
p-value: p=0.003
QTc dispersion calculated from three specific leads may be as useful as the standard 12-lead measurement for prognostic assessment after myocardial infarction, offering greater simplicity.
Glancy et al. (1995) conducted an observational in Myocardial infarction (n=270). Three-lead measurement of QTc dispersion vs. Standard 12-lead measurement was evaluated on Difference in the fall in QTc dispersion from early to late ECG between deaths and survivors (p=0.003). Three-lead measurement of QTc dispersion using quasi-orthogonal leads successfully differentiated post-MI deaths from survivors (-2.6 vs 26.9 msec; P=0.003), similar to standard 12-lead ECGs.
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