Key result
HCM requires lifelong management for progressive LV remodeling, heart failure, and arrhythmias.
Why the study?
Despite extensive focus on genetics, left ventricular tract obstruction, and sudden cardiac death prevention in HCM, there is a need to recognize its heterogeneity and lifelong management needs.
This review highlights that hypertrophic cardiomyopathy is a heterogeneous condition requiring lifelong management due to progressive left ventricular remodeling and diverse clinical trajectories.
Answers are grounded in this paper and cite their sources.
Emphasizes lifelong HCM surveillance amid heterogeneity; leaves open phenotype-specific strategies to mitigate remodeling.
Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary cardiomyopathy, showing an autosomal-dominant f inheritance. A great deal of attention has been paid to genetics, left ventricular tract obstruction and the prediction and prevention of sudden cardiac death in HCM. Needless to say, these are very important, but we should recognize the heterogeneity in etiology, morphology, clinical course and management of this unique cardiomyopathy. Another important perspective is that HCM causes left ventricular remodeling over time and is a disease that requires lifelong management in the real world.
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Kitaoka et al. (2020) conducted a review in Hypertrophic Cardiomyopathy. Hypertrophic cardiomyopathy is a heterogeneous and lifelong disease characterized by progressive left ventricular remodeling, requiring long-term management for heart failure and arrhythmias.
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