In a cohort of 1122 patients, female gender was not an independent risk factor for in-hospital or 3-year mortality after myocardial infarction following adjustment for baseline differences.
Cohort (n=1,122)
Does female gender independently impact survival after myocardial infarction compared to male gender?
Higher observed mortality rates in women following myocardial infarction are driven by baseline risk factors rather than gender being an independent risk factor.
To examine the impact of gender on survival after myocardial infarction, we performed a retrospective cohort study of 332 women and 790 men. Women who had a myocardial infarction were older and more often had hypertension, diabetes, previous heart failure, and impaired left ventricular function on admission. Cumulative 3-year mortality and in-hospital mortality rates were significantly higher in women than men, but mortality among hospital survivors was similar. After multivariate adjustment for baseline differences, mortality rates were not significantly different between women and men for in-hospital deaths, and mortality at 3 years among hospital survivors tended to be lower among women. We conclude that higher observed mortality rates following a myocardial infarction in women are related to differences in known risk factors for subsequent mortality and that gender should not be considered an independent risk factor for mortality after myocardial infarction.
Nicholas H. Fiebach (1990) conducted a cohort in Myocardial infarction (n=1,122). Female gender vs. Male gender was evaluated on In-hospital and 3-year mortality. In a cohort of 1122 patients, female gender was not an independent risk factor for in-hospital or 3-year mortality after myocardial infarction following adjustment for baseline differences.
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