Key result
Women had a significantly greater risk of death at 28 days following a first acute myocardial infarction compared to men (adjusted OR 1.72; 95% CI 1.12-2.65).
Why the study?
Does female sex increase the risk of mortality and readmission following a first acute myocardial infarction compared to male sex?
Population
1,460 consecutive patients aged 80 years or younger with a first acute myocardial infarction from four…
Comparison
Female sex (observational comparison) vs Male sex
Design
Cohort
Follow-up
6 months
Authors
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Women with first AMI warrant heightened short-term vigilance; observational data leaves open whether sex-specific interventions alter outcomes.
Cohort (n=1,460)
Yes
Does female sex increase the risk of mortality and readmission following a first acute myocardial infarction compared to male sex?
Effect estimate: OR 1.72 (95% CI 1.12-2.65)
Absolute Event Rate: 18.5% vs 8.3%
p-value: p=<.001
Women experience significantly higher short- and medium-term mortality following a first acute myocardial infarction compared to men, even after adjusting for age and baseline comorbidities.
Jaume Marrugat (1998) conducted a cohort in first acute myocardial infarction (n=1,460). Female sex vs. Male sex was evaluated on 28-day mortality (OR 1.72, 95% CI 1.12-2.65, p=<.001). Women had a significantly greater risk of death at 28 days following a first acute myocardial infarction compared to men (adjusted OR 1.72; 95% CI 1.12-2.65).
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