Sex differences in survival after myocardial infarction in Sweden. Data from the Swedish National Acute Myocardial Infarction register
Key result
Women under 50 years of age with acute myocardial infarction had significantly higher 28-day (OR 1.31) and 1-year mortality (OR 1.37) compared to men of the same age.
Why the study?
Does female sex impact pre-hospital, 28-day, and 1-year mortality after acute myocardial infarction compared to male sex?
Population
353,905 cases of acute myocardial infarction occurring between 1987 and 1995 in Swedish men and women aged…
Comparison
Female sex vs Male sex
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
May warrant closer monitoring of younger women with MI; leaves open whether diabetes mediates the observed mortality association.
Structured PICO
Does female sex impact pre-hospital, 28-day, and 1-year mortality after acute myocardial infarction compared to male sex?
P
Population
353,905 cases of acute myocardial infarction occurring between 1987 and 1995 in Swedish men and women aged 30 to 89 years.
I
Intervention
Female sex
C
Comparator
Male sex
O
Outcome
Mortality outside hospital, 28-day mortality, and 1-year mortalityhard clinical
Women under 50 years of age have a consistently worse prognosis than men after acute myocardial infarction, largely associated with diabetes, whereas older women have a survival advantage.
Cite This Study
Annika Rosengren (2001) studied this question. Women under 50 years of age with acute myocardial infarction had significantly higher 28-day (OR 1.31) and 1-year mortality (OR 1.37) compared to men of the same age.