Key result
Female gender was associated with a higher unadjusted 5-year mortality rate after AMI compared to men (61% vs 48%, p<0.001), but was not an independent predictor after adjusting for confounders.
Why the study?
Does female gender independently influence 5-year mortality and prognosis after acute myocardial infarction compared to male gender?
Cohort (n=862)
No
Does female gender independently influence 5-year mortality and prognosis after acute myocardial infarction compared to male gender?
Absolute Event Rate: 61% vs 48%
p-value: p=<0.001
Although women have a higher crude 5-year mortality after acute myocardial infarction than men, this difference is driven by age and baseline cardiovascular comorbidities rather than female gender being an independent risk factor.
No takes yet. Share an insight, caveat, or question.
Women’s higher unadjusted post-AMI mortality reflects age and comorbidities, not gender itself; leaves open residual gender effects after full adjustment.
Herlitz et al. (1996) conducted a cohort in Acute myocardial infarction (n=862). Female gender vs. Male gender was evaluated on 5-year mortality rate (p=<0.001). Female gender was associated with a higher unadjusted 5-year mortality rate after AMI compared to men (61% vs 48%, p<0.001), but was not an independent predictor after adjusting for confounders.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: