Why the study?
Comparative data regarding chronic lesion durability across different pulsed field ablation platforms remain limited.
Does the balloon-in-basket pulsed field ablation catheter improve chronic pulmonary vein isolation durability compared to the pentaspline catheter in patients with atrial fibrillation?
Cohort (n=132)
Yes
Does the balloon-in-basket pulsed field ablation catheter improve chronic pulmonary vein isolation durability compared to the pentaspline catheter in patients with atrial fibrillation?
Absolute Event Rate: 2.9% vs 28.1%
p-value: p=0.003
The balloon-in-basket PFA platform demonstrated significantly greater chronic pulmonary vein isolation durability compared to the pentaspline system, although clinical recurrence rates did not significantly differ.
May guide PFA catheter selection; leaves open randomized trials to confirm durability differences.
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Kakarla et al. (2026) conducted a cohort in Atrial fibrillation (n=132). Balloon-in-basket PFA catheter (VOLT) vs. Pentaspline PFA catheter (FARAPULSE) was evaluated on PV-level reconnection (p=0.003).
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