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April 22, 2019Current Aging ScienceOpen Access

Impact of Cardiovascular Factors on Pulse Wave Velocity and Total Vascular Resistance in Different Age Group Patients with Cardiovascular Disorders

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Key result

Older age, systolic BP, and heart rate link to higher PWV, while BMI links inversely.

  • n=782

Why the study?

The study was designed to investigate the influence of different cardiovascular factors on arterial stiffness and vascular resistance in patients with cardiovascular disease from an eastern Indian population.

Population

782 CVD patients aged between 15 to 87 years from an eastern India population

Design

Community-based observational study

Authors

AGAmit GhoshIndian Institute of Technology MadrasADAbhijith DharmarajanAll India Institute of Medical Sciences BhubaneswarPSPrafulla Kumar SwainSiksha O Anusandhan University

Discussion

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Implication

Should not yet guide arterial stiffness assessment in CVD; leaves open longitudinal validation of these correlates.

Study Design

Type

Observational (n=782)

Structured PICO

P
Population
782 patients with Cardiovascular Disease (hypertension n=460, Ischemic Heart Disease n=152, Congestive cardiac failure n=155, Peripheral Arterial Disease n=15) aged 15 to 87 years from eastern India.
O
Outcome
Influence of different cardiovascular factors on arterial stiffness (Pulse Wave Velocity) and vascular resistance (Total Vascular Resistance)surrogate

In patients with cardiovascular disease, age over 55 years has the greatest impact on pulse wave velocity, while systolic blood pressure, heart rate, and body surface area also show significant positive associations with arterial stiffness.

Limitations

  • Unequal number of male and female participants
  • Wide variation of the age of the subjects
  • Analyzing association of many factors at a time
  • unequal number of male and female participants
  • wide variation of the age of the subjects
  • analyzing association of many factors at a time

Cite This Study

Ghosh et al. (2019) conducted an observational in Cardiovascular Disease (n=782). In 782 patients with cardiovascular disease, older age (>55 years), systolic blood pressure, and heart rate were positively associated with pulse wave velocity, while BMI had a negative impact.

synapsesocial.com/papers/6a0ac67e6f9280a32b5cf6bbhttps://doi.org/10.2174/1874609812666190226151500

Topics

Women and heart diseaseHypertension management
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Also Consider

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