Key result
Continuous intravenous infusion of insulin reduced total mortality from 42% to 17% (p<0.05) compared to standard care in diabetic patients with acute myocardial infarction.
Why the study?
Does continuous intravenous infusion of insulin reduce mortality in diabetic patients with acute myocardial infarction?
Observational (n=62)
Does continuous intravenous infusion of insulin reduce mortality in diabetic patients with acute myocardial infarction?
Absolute Event Rate: 17% vs 42%
p-value: p=<0.05
Continuous intravenous insulin infusion to maintain strict blood glucose control significantly reduces mortality and arrhythmias in diabetic patients with acute myocardial infarction compared to standard subcutaneous insulin or oral therapies.
No takes yet. Share an insight, caveat, or question.
Should not yet change practice; hypothesis-generating for insulin infusion in diabetic AMI pending RCTs.
Clark et al. (1985) conducted an observational in Diabetics with acute myocardial infarction (n=62). Continuous intravenous infusion of insulin vs. Standard care (diet, oral hypoglycaemic drugs, or subcutaneous insulin) was evaluated on Total mortality (p=<0.05). Continuous intravenous infusion of insulin reduced total mortality from 42% to 17% (p<0.05) compared to standard care in diabetic patients with acute myocardial infarction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: