Key result
Diabetic patients treated with insulin (79%) or oral hypoglycaemic agents (73%) had significantly increased 7-year mortality post-MI compared to non-diabetic patients (46%).
Why the study?
Does the presence of diabetes and its specific treatment regimen affect long-term mortality in patients with acute myocardial infarction?
Cohort (n=6,676)
Does the presence of diabetes and its specific treatment regimen affect long-term mortality in patients with acute myocardial infarction?
Diabetic patients with acute myocardial infarction, particularly those requiring insulin or oral hypoglycemic agents, receive less thrombolysis and have significantly higher long-term mortality compared to non-diabetic patients.
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May inform risk stratification in diabetic MI survivors; hypothesis-generating for therapy-specific effects on long-term survival.
Finn Gustafsson (2000) conducted a cohort in Acute myocardial infarction and diabetes (n=6,676). Antidiabetic treatment regimens (insulin, oral hypoglycaemic agents, diet only) vs. Patients without diabetes was evaluated on 7-year mortality. Diabetic patients treated with insulin (79%) or oral hypoglycaemic agents (73%) had significantly increased 7-year mortality post-MI compared to non-diabetic patients (46%).
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