What question did this study set out to answer?

To develop specialized stature and weight centile growth charts for home-reared children with Down syndrome from age 1 month to 18 years.

January 1, 1988PEDIATRICS

Growth Charts for Children With Down Syndrome: 1 Month to 18 Years of Age

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Authors

CCChristine E. CronkChildren's Hospital of Wisconsin ACAllen C. CrockerTufts University SPSiegfried M. PueschelTufts University

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Implication

Observational study reveals specialized growth trajectories in children with Down syndrome, highlighting distinct patterns in stature, weight, and cardiac disease impact.

Key Points

To develop specialized stature and weight centile growth charts for home-reared children with Down syndrome from age 1 month to 18 years.
Analyzed 4,650 growth observations collected from 730 home-reared children with Down syndrome.
Calculated five smoothed centiles across two age intervals (1 to 36 months and 2 to 18 years) using a flexible mathematical function.
Assessed growth differences based on history of moderate or severe congenital heart disease and compared measurements to institutionalized cohorts.
Growth rates were persistently reduced across childhood, with the most pronounced deficits occurring in infancy and adolescence.
Children with moderate to severe congenital heart disease were on average 1.5 to 2.0 cm shorter and approximately 1 kg lighter than those with mild or no heart disease.
Home-reared children were taller across all ages than previously studied institutionalized cohorts, while demonstrating an increased tendency to be overweight starting in late infancy.

Cite This Study

Cronk et al. (1988) studied this question.

synapsesocial.com/papers/6a0b01889b4eb2f7ce2e3ea4 https://doi.org/10.1542/peds.81.1.102

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Implication

Observational study reveals specialized growth trajectories in children with Down syndrome, highlighting distinct patterns in stature, weight, and cardiac disease impact.

Growth Charts for Children With Down Syndrome: 1 Month to 18 Years of Age

Discussion

Member takes

Implication

Key Points

Cite This Study

Growth Charts for Children With Down Syndrome: 1 Month to 18 Years of Age

Discussion

Member takes

Implication

Key Points

Cite This Study

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