Key result
Among patients with complicated hypertension, both undersupply and oversupply of antihypertensive drugs were associated with a 15% (p=0.009) and 16% (p<0.0001) greater probability of hospitalization.
Why the study?
Does undersupply or oversupply of antihypertensive drugs increase hospitalization and health care costs in adults with hypertension?
Observational (n=15,206)
No
Does undersupply or oversupply of antihypertensive drugs increase hospitalization and health care costs in adults with hypertension?
Effect estimate: 15% greater probability (undersupply); 16% greater probability (oversupply)
p-value: p=0.009 (undersupply); <0.0001 (oversupply)
Both undersupply and oversupply of antihypertensive medications are associated with increased hospitalization rates in patients with complicated hypertension.
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Supports supply monitoring in complicated hypertension; leaves open whether optimizing supply reduces hospitalizations.
Stroupe et al. (2006) conducted an observational in Hypertension (n=15,206). Antihypertensive drug refill adherence (undersupply or oversupply) vs. Appropriate supply (80-120% of supplies needed) was evaluated on Hospitalization and health care costs (15% greater probability (undersupply); 16% greater probability (oversupply), p=0.009 (undersupply); <0.0001 (oversupply)). Among patients with complicated hypertension, both undersupply and oversupply of antihypertensive drugs were associated with a 15% (p=0.009) and 16% (p<0.0001) greater probability of hospitalization.