Key result
LBBP drives clinical recovery in a single patient with end-stage HCM and complete LBBB.
Why the study?
Complete LBBB in end-stage hypertrophic cardiomyopathy is linked to poor outcomes, and previous research suggested biventricular pacing has limited effects in such patients.
Does left bundle branch pacing improve outcomes in patients with end-stage hypertrophic cardiomyopathy and complete left bundle branch block?
Case Report (n=1)
Does left bundle branch pacing improve outcomes in patients with end-stage hypertrophic cardiomyopathy and complete left bundle branch block?
Left bundle branch pacing may be a viable therapeutic option for patients with end-stage hypertrophic cardiomyopathy and complete left bundle branch block, a population where biventricular pacing has historically shown limited effects.
Hypothesis-generating for left bundle branch pacing in end-stage hypertrophic cardiomyopathy with left bundle branch block; prospective trials needed.
Patients with hypertrophic cardiomyopathy (HCM) enter the terminal stage when developed left ventricle enlargement and ejection fraction (EF) reduction. The concomitant complete left bundle branch block (LBBB) is considered an important factor related to poor outcome. Previous research suggested that biventricular pacing has limited effects on such patients. We report a case with end-stage hypertrophic cardiomyopathy who had a miraculous recovery after receiving successful left bundle branch pacing (LBBP).
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Lin et al. (2025) conducted a case report in End-stage hypertrophic cardiomyopathy (n=1). Left bundle branch pacing (LBBP) was evaluated on Clinical recovery. Left bundle branch pacing resulted in a miraculous recovery in a single patient with end-stage hypertrophic cardiomyopathy and complete left bundle branch block.
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