TLR ligand sensing by lymph node FRCs directs intranodal lymphocyte accumulation to promote immune responses

This is the authors' abstract. We don't add key points for this paper.

cells, reduced the number of lymphocytes recruited into the immune response limiting vaccine efficacy against tumors. Taken together, these observations provide further evidence for a critical role of early FRC activation in driving effective immunity, placing these non-hematopoietic cells at the center of adaptive host protection.