Key result
The percentage of phosphorylated cardiac troponin I (cTnI1) is significantly lower in failing human hearts compared to normal hearts (P<.00).
Authors
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May indicate altered myofilament function in HF; leaves open its value as biomarker or therapeutic target.
Observational (n=44)
p-value: p=<.00
Bodor et al. (1997) conducted an observational in Heart failure (n=44). Failing myocardium vs. Normal myocardium was evaluated on Percentage of cTnI made up of cTnI1 (phosphorylated form of TnI) (p=<.00). The percentage of phosphorylated cardiac troponin I (cTnI1) is significantly lower in failing human hearts compared to normal hearts (P<.00).
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