Key result
Lung resection linked to a ~2% LVEF drop and higher tricuspid pressure.
Why the study?
Changes in heart structure and function after lung resection in lung cancer patients are challenging to manage, making a non-invasive and reliable measurement tool critical.
Does lung resection alter heart structure and function as measured by tissue Doppler imaging in patients with lung cancer?
Observational (n=43)
No
Does lung resection alter heart structure and function as measured by tissue Doppler imaging in patients with lung cancer?
Absolute Event Rate: 64.91% vs 67.02%
p-value: p=0.04
Lung resection via lobectomy leads to measurable structural and functional cardiac changes, including decreased LVEF and increased tricuspid pressure, though LV filling pressure remains preserved.
No takes yet. Share an insight, caveat, or question.
Should not yet alter lung resection protocols; leaves open prognostic relevance and need for prospective trials.
Chen et al. (2023) conducted an observational in Lung cancer (non-small cell lung cancer and metastatic lung cancer) (n=43). Lung resection (lobectomy) vs. Preoperative baseline was evaluated on Left ventricular ejection fraction (LVEF) (p=0.04). Lung resection significantly decreased left ventricular ejection fraction from 67.02% to 64.91% and increased tricuspid pressure, while preserving left ventricular filling pressure.
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