Key result
Single-beat aortic pressure Emax tracking yields ~0.79 correlation with conventional methods in animals.
Population
Animal models undergoing inotropic interventions
Comparison
Emax estimation from a single beat of an aortic… vs Conventional Emax measurement method involving…
Design
Preclinical
Authors
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Supports feasibility of single-beat Emax tracking in animals; leaves open clinical translation and human validation.
Effect estimate: correlation coefficient 0.793
A novel technique for tracking Emax from a single beat of an aortic pressure waveform showed good correlation with conventional methods in animal models, potentially enabling less invasive monitoring of contractility.
Gao et al. (2014) studied this question. Aortic pressure waveform analysis for Emax tracking vs. Conventional Emax measurement method (multiple ventricular pressure-volume loops) was evaluated on Correlation of estimated Emax changes with reference changes (correlation coefficient 0.793). Tracking Emax from a single beat of an aortic pressure waveform correlated well with the conventional measurement method in animals (correlation coefficient 0.793).
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