Key result
In IAA-N2-treated cat papillary muscle, CP utilization increased from 0.68 micromole/g/min at rest to 1.07 micromole/g/min with passive stretch, with a mechanochemical coupling efficiency of 33%.
Absolute Event Rate: 1.07% vs 0.68%
In IAA-N2-treated cat papillary muscle, CP utilization is proportional to the number of activations and contractile element work, with a mechanochemical coupling efficiency of 33%.
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Requires validation before human extrapolation; extends animal data on cardiac mechanochemistry.
Pool et al. (1967) studied cat papillary muscle (experimental model). passive stretch and isometric contraction vs. resting without tension was evaluated on creatine phosphate (CP) utilization. In IAA-N2-treated cat papillary muscle, CP utilization increased from 0.68 micromole/g/min at rest to 1.07 micromole/g/min with passive stretch, with a mechanochemical coupling efficiency of 33%.
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